4Y6M
Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Plasmepsin-2 | polymer | 329 | 36953.7 | 3 | UniProt (P46925) Pfam (PF00026) In PDB | Plasmodium falciparum | Aspartic hemoglobinase II,PFAPD |
| 2 | A, B, C | ~{N}1-[(~{Z},3~{R})-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-but-1-en-2-yl]-5-piperidin-1-yl-~{N}3,~{N}3-dipropyl-benzene-1,3-dicarboxamide | non-polymer | 640.9 | 3 | Chemie (48Q) | |||
| 3 | A, B, C | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 110861.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2475.1 | |
| All* | Total formula weight | 113336.3 |
