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4Y6L

Human SIRT2 in complex with myristoylated peptide (H3K9myr)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD-dependent protein deacetylase sirtuin-2polymer29333201.22UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (Human)Regulatory protein SIR2 homolog 2,SIR2-like protein 2
2C, D
(C, D)
peptide THR-ALA-ARG-MYK-SER-THR-GLYpolymer7931.22UniProt (by SIFTS) (P68431)Homo sapiens
3E, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4G, H, I, J
(A, B, C, D)
waterwater18.0522Chemie (HOH)
Sequence modifications
A, B: 52 - 356 (UniProt: Q8IXJ6)
PDBExternal DatabaseDetails
-Gln 292deletion
-Ser 293deletion
-Asp 294deletion
-Pro 295deletion
-Phe 296deletion
-Leu 297deletion
-Gly 298deletion
-Met 299deletion
-Ile 300deletion
-Met 301deletion
-Gly 302deletion
-Leu 303deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight68264.8
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight68395.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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