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4Y3O

Crystal structure of Ribosomal oxygenase NO66 in complex with substrate Rpl8 peptide and Ni(II) and cofactor N-oxalyglycine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66polymer46652984.82UniProt (Q9H6W3)
Pfam (PF08007)
Pfam (PF21233)
Homo sapiens (Human)60S ribosomal protein L8 histidine hydroxylase,Histone lysine demethylase NO66,Myc-associated protein with JmjC domain,Nucleolar protein 66,hsNO66,Ribosomal oxygenase NO66,ROX
2C, D
(C, D)
Rpl8 peptidepolymer111104.22UniProt (by SIFTS) (P62917)Homo sapiens
3E, G
(A, B)
NICKEL (II) IONnon-polymer58.72Chemie (NI)
4F, H
(A, B)
N-OXALYLGLYCINEnon-polymer147.12Chemie (OGA)
5I, J, K
(B)
GLYCEROLnon-polymer92.13Chemie (GOL)
6L
(B)
ACETATE IONnon-polymer59.01Chemie (ACT)
7M, N, O, P
(A, B, C, D)
waterwater18.0563Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight108178.1
Non-Polymers*Number of molecules8
Total formula weight746.9
All*Total formula weight108925.0
*Water molecules are not included.

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PDB entries from 2025-12-31

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