4XYK
Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | ATP-dependent 6-phosphofructokinase, platelet type | polymer | 812 | 89144.7 | 4 | UniProt (Q01813) Pfam (PF00365) In PDB | Homo sapiens (Human) | PFK-P,6-phosphofructokinase type C,Phosphofructo-1-kinase isozyme C,PFK-C,Phosphohexokinase |
2 | A, B, C, D | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
3 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 12 | Chemie (PO4) |
Sequence modifications
A, B, C, D: 1 - 784 (UniProt: Q01813)
PDB | External Database | Details |
---|---|---|
Met -27 | - | initiating methionine |
Ser -26 | - | expression tag |
Tyr -25 | - | expression tag |
Tyr -24 | - | expression tag |
His -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
Asp -17 | - | expression tag |
Tyr -16 | - | expression tag |
Asp -15 | - | expression tag |
Ile -14 | - | expression tag |
Pro -13 | - | expression tag |
Thr -12 | - | expression tag |
Thr -11 | - | expression tag |
Glu -10 | - | expression tag |
Asn -9 | - | expression tag |
Leu -8 | - | expression tag |
Tyr -7 | - | expression tag |
Phe -6 | - | expression tag |
Gln -5 | - | expression tag |
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Asp -1 | - | expression tag |
Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 356578.9 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 2848.5 | |
All* | Total formula weight | 359427.4 |