4XWK

P-glycoprotein co-crystallized with BDE-100

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Multidrug resistance protein 1A	polymer	1284	141920.0	1	UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB	Mus musculus (Mouse)	ATP-binding cassette sub-family B member 1A,MDR1A,Multidrug resistance protein 3,P-glycoprotein 3
2	A	2,4-dibromophenyl 2,4,6-tribromophenyl ether	non-polymer		564.7	1	Chemie (4C8)

Sequence modifications

A: 1 - 1276 (UniProt: P21447)

PDB	External Database	Details
Gln 83	Asn 83	engineered mutation
Gln 87	Asn 87	engineered mutation
Gln 90	Asn 90	engineered mutation
Leu 1277	-	expression tag
Glu 1278	-	expression tag
His 1279	-	expression tag
His 1280	-	expression tag
His 1281	-	expression tag
His 1282	-	expression tag
His 1283	-	expression tag
His 1284	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	141920.0
Non-Polymers*	Number of molecules	1
	Total formula weight	564.7
All*	Total formula weight	142484.6

*Water molecules are not included.