4XNW

The human P2Y1 receptor in complex with MRS2500

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	P2Y purinoceptor 1,Rubredoxin,P2Y purinoceptor 1	polymer	421	47468.3	2	UniProt (P47900) UniProt (P00268) Pfam (PF00001) Pfam (PF00301) In PDB	Homo sapiens (Human)	P2Y1, ATP receptor, Purinergic receptor, Rd
2	A, C	[(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hex-1-yl]methyl dihydrogen phosphate	non-polymer		561.2	2	Chemie (2ID)
3	A, C	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4		water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, C: 2 - 247 (UniProt: P47900)
A, C: 1001 - 1054 (UniProt: P00268)
A, C: 253 - 373 (UniProt: P47900)

PDB	External Database	Details
Asn 320	Asp 320	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94936.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1253.1
All*	Total formula weight	96189.7

*Water molecules are not included.