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4XLS

Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, G, H
(A, B, G, H)
DNA-directed RNA polymerase subunit alphapolymer31434830.94UniProt (Q9KWU8)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
Thermus aquaticusRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C, I
(C, I)
DNA-directed RNA polymerase subunit betapolymer1119124930.02UniProt (Q9KWU7)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Pfam (PF04560)
Thermus aquaticusRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D, J
(D, J)
DNA-directed RNA polymerase subunit beta'polymer1524171187.52UniProt (Q9KWU6)
Pfam (PF04997)
Pfam (PF21668)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Thermus aquaticusRNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4E, K
(E, K)
DNA-directed RNA polymerase subunit omegapolymer9911642.42UniProt (Q9EVV4)
Pfam (PF01192)
Thermus aquaticusRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5F, L
(F, L)
RNA polymerase sigma factor SigApolymer34739864.72UniProt (Q9EZJ8)
Pfam (PF00140)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
Thermus aquaticus
6M, N
(M, N)
CarD-like transcriptional regulatorpolymer16418316.02UniProt (H9ZP94)
Pfam (PF02559)
Pfam (PF21095)
Thermus thermophilus JL-18
7O, Q
(O, R)
DNA (30-MER)polymer309236.02synthetic constructDNA non-template strand
8P, R
(P, S)
DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3')polymer247327.82synthetic constructDNA template strand
9S, T, V, W
(D, J)
ZINC IONnon-polymer65.44Chemie (ZN)
10U, X
(D, J)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight904332.5
Non-Polymers*Number of molecules6
Total formula weight310.2
All*Total formula weight904642.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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