4XKI

Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Fibroblast growth factor 1	polymer	147	16888.1	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (Human)	FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1
2	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A, B	PHOSPHATE ION	non-polymer		95.0	8	Chemie (PO4)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	B	NONAETHYLENE GLYCOL	non-polymer		414.5	1	Chemie (2PE)
6		water	water		18.0	260	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
Met 0	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Arg 116	Ser 131	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33776.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1458.5
All*	Total formula weight	35234.6

*Water molecules are not included.