4XI9
Human OGT in complex with UDP-5S-GlcNAc and substrate peptide (RBL2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 4 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (Human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | E, F, G, H (E, F, G, H) | Retinoblastoma-like protein 2 | polymer | 8 | 744.8 | 4 | UniProt (Q08999) | Homo sapiens | 130 kDa retinoblastoma-associated protein,p130,Retinoblastoma-related protein 2,RBR-2,pRb2 |
| 3 | I, J, K, L (A, B, C, D) | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | non-polymer | 623.4 | 4 | Chemie (12V) |
Sequence modifications
A, B, C, D: 313 - 1031 (UniProt: O15294)
E, F, G, H: 1416 - 1422 (UniProt: Q08999)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 1423 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 326877.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2493.7 | |
| All* | Total formula weight | 329371.0 |
