4XFT
Structure of IL-18 SER Mutant III
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-18 | polymer | 157 | 18023.4 | 2 | UniProt (Q14116) Pfam (PF00340) | Homo sapiens (Human) | IL-18,Iboctadekin,Interferon gamma-inducing factor,IFN-gamma-inducing factor,Interleukin-1 gamma,IL-1 gamma |
| 2 | C, D (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 157 (UniProt: Q14116)
| PDB | External Database | Details |
|---|---|---|
| Ala 67 | Lys 103 | engineered mutation |
| Ala 69 | Glu 105 | engineered mutation |
| Ala 70 | Lys 106 | engineered mutation |
| Ala 71 | Ile 107 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36046.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 156.3 | |
| All* | Total formula weight | 36203.1 |
