4XFT

Structure of IL-18 SER Mutant III

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Interleukin-18	polymer	157	18023.4	2	UniProt (Q14116) Pfam (PF00340) In PDB	Homo sapiens (Human)	IL-18,Iboctadekin,Interferon gamma-inducing factor,IFN-gamma-inducing factor,Interleukin-1 gamma,IL-1 gamma
2	B	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
3		water	water		18.0	168	Chemie (HOH)

Sequence modifications

A, B: 1 - 157 (UniProt: Q14116)

PDB	External Database	Details
Ala 67	Lys 103	engineered mutation
Ala 69	Glu 105	engineered mutation
Ala 70	Lys 106	engineered mutation
Ala 71	Ile 107	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36046.8
Non-Polymers*	Number of molecules	2
	Total formula weight	156.3
All*	Total formula weight	36203.1

*Water molecules are not included.