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4XCF

Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
4E10 Fab light chainpolymer21523395.81Homo sapiens
2B
(H)
4E10 Fab heavy chainpolymer22823990.01Homo sapiens
3C
(P)
MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683polymer162226.61UniProt (by SIFTS) (P05877)Human immunodeficiency virus 1
4D, E, F, G
(L, H)
[(2R)-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoatenon-polymer370.44Chemie (43Y)
5H, I, J
(L, H, P)
waterwater18.0611Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight49612.5
Non-Polymers*Number of molecules4
Total formula weight1481.4
All*Total formula weight51093.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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