4XCF

Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC)

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue 43Y L 301

Chain	Residue
H	43Y301
L	GLY9
L	THR10
L	GLN100
L	GLY101
L	HOH414
L	HOH432
L	HOH539

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site_id	AC2
Number of Residues	5
Details	binding site for residue 43Y L 302

Chain	Residue
L	THR109
L	LYS169
L	ASP170
L	SER171
L	ARG108

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site_id	AC3
Number of Residues	11
Details	binding site for residue 43Y H 301

Chain	Residue
H	THR116
H	LYS117
H	GLY118
H	PRO214
H	SER215
H	ASN216
H	THR217
H	HOH439
H	HOH450
L	43Y301
L	HOH418

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site_id	AC4
Number of Residues	11
Details	binding site for residue 43Y H 302

Chain	Residue
H	SER7
H	THR19
H	THR70
H	TYR79
H	GLU81
H	HOH429
L	GLN27
L	SER27
L	SER67
L	GLY68
L	THR69

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR206-HIS212
L	TYR192-HIS198

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