4XAR
mGluR2 ECD and mGluR3 ECD complex with ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metabotropic glutamate receptor 3 | polymer | 517 | 58776.6 | 1 | UniProt (Q14832) Pfam (PF01094) | Homo sapiens (Human) | mGluR3 |
| 2 | B (A) | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid | non-polymer | 185.2 | 1 | Chemie (40F) PubChem (114827) PubChem (213056) PubChem (6101858) PubChem (10702665) PubChem (10845212) PubChem (44322702) PubChem (45098631) PubChem (50989828) PubChem (156666) PubChem (15408708) PubChem (89156372) PubChem (89651893) PubChem (90488818) PubChem (90936348) PubChem (90981390) PubChem (92403463) PubChem (98137211) PubChem (99722638) PubChem (99722640) PubChem (101932822) PubChem (102066259) PubChem (121226785) PubChem (124560124) PubChem (130820172) PubChem (130976542) PubChem (131013715) PubChem (139025891) PubChem (146157633) PubChem (154825295) | |||
| 3 | C, D, E, F, G... (A) | IODIDE ION | non-polymer | 126.9 | 8 | Chemie (IOD) PubChem (30165) | |||
| 4 | K (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 2 - 508 (UniProt: Q14832)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Ala 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Ser 240 | Cys 240 | engineered mutation |
| Glu 508 | Gln 508 | engineered mutation |
| Gly 509 | - | expression tag |
| His 510 | - | expression tag |
| His 511 | - | expression tag |
| His 512 | - | expression tag |
| His 513 | - | expression tag |
| His 514 | - | expression tag |
| His 515 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58776.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1200.4 | |
| All* | Total formula weight | 59977.0 |
