4XAR

mGluR2 ECD and mGluR3 ECD complex with ligands

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Metabotropic glutamate receptor 3	polymer	517	58776.6	1	UniProt (Q14832) Pfam (PF01094) In PDB	Homo sapiens (Human)	mGluR3
2	A	(1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid	non-polymer		185.2	1	Chemie (40F)
3	A	IODIDE ION	non-polymer		126.9	8	Chemie (IOD)
4		water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 2 - 508 (UniProt: Q14832)

PDB	External Database	Details
Met -1	-	initiating methionine
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 240	Cys 240	engineered mutation
Glu 508	Gln 508	engineered mutation
Gly 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58776.6
Non-Polymers*	Number of molecules	9
	Total formula weight	1200.4
All*	Total formula weight	59977.0

*Water molecules are not included.