4XAR

mGluR2 ECD and mGluR3 ECD complex with ligands

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue 40F A 601

Chain	Residue
A	ARG64
A	ASP301
A	LYS389
A	HOH736
A	ARG68
A	SER149
A	TYR150
A	SER151
A	ALA172
A	SER173
A	THR174
A	TYR222

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 602

Chain	Residue
A	SER152

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site_id	AC3
Number of Residues	1
Details	binding site for residue IOD A 603

Chain	Residue
A	GLN67

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site_id	AC4
Number of Residues	4
Details	binding site for residue IOD A 604

Chain	Residue
A	THR98
A	SER149
A	TYR150
A	VAL153

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site_id	AC5
Number of Residues	1
Details	binding site for residue IOD A 606

Chain	Residue
A	ILE438

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site_id	AC6
Number of Residues	1
Details	binding site for residue IOD A 608

Chain	Residue
A	ARG352

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site_id	AC7
Number of Residues	3
Details	binding site for residue IOD A 609

Chain	Residue
A	SER255
A	ASP257
A	TYR343

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Functional Information from PROSITE/UniProt

site_id	PS00979
Number of Residues	19
Details	G_PROTEIN_RECEP_F3_1 G-protein coupled receptors family 3 signature 1. VaNLLrLFqIPQISyASTS

Chain	Residue	Details
A	VAL157-SER175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	SER151
A	ALA172
A	TYR222
A	ASP301
A	LYS389

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN209
A	ASN292
A	ASN414
A	ASN439

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