4XAJ
Crystal structure of human NR2E1/TLX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, C, B, D) | Maltose-binding periplasmic protein,Nuclear receptor subfamily 2 group E member 1 | polymer | 576 | 63539.4 | 4 | UniProt (P0AEY0) UniProt (Q9Y466) Pfam (PF01547) Pfam (PF00104) | Escherichia coli O157:H7 | MBP,MMBP,Maltodextrin-binding protein,Nuclear receptor TLX,Protein tailless homolog,hTll |
| 2 | C, F (Q, P) | Atrophin/grunge | polymer | 18 | 2090.3 | 2 | UniProt (Q8IQA6) UniProt (by SIFTS) (M9PHT1) | DROSOPHILA MELANOGASTER | |
| 3 | G, H, I, J (E, F, G, H) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose |
Sequence modifications
A, C, B, D: 2 - 368 (UniProt: P0AEY0)
A, C, B, D: 1182 - 1383 (UniProt: Q9Y466)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Asn 369 | - | linker |
| Ala 370 | - | linker |
| Ala 371 | - | linker |
| Ala 372 | - | linker |
| Glu 373 | - | linker |
| Phe 374 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Arg 1257 | Lys 294 | engineered mutation |
| Thr 1259 | Asn 296 | engineered mutation |
| Leu 1260 | Lys 297 | engineered mutation |
| Val 1338 | Cys 375 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 258338.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| All* | Total formula weight | 259707.4 |
