4XA5
Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming 8-oxo-dGTP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase lambda | polymer | 325 | 36552.6 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB | Homo sapiens (Human) | Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa |
2 | D | DOWNSTREAM PRIMER DNA (5'-D(P*GP*CP*CP*G)-3') | polymer | 4 | 1191.8 | 1 | synthetic construct | ||
3 | P | PRIMER DNA (5'-D(*CP*AP*GP*TP*AP*(DOC))-3') | polymer | 6 | 1777.2 | 1 | synthetic construct | ||
4 | T | TEMPLATE DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3') | polymer | 11 | 3374.2 | 1 | synthetic construct | ||
5 | A | 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (8DG) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
7 | A | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 42895.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 933.1 | |
All* | Total formula weight | 43828.9 |