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4X8T

FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-chloro-3,4-dihydroisoquinolin-1(2H)-one

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Factor VIIa (Heavy Chain)polymer25428103.31UniProt (P08709)
Pfam (PF00089)
Homo sapiens (Human)Proconvertin,Serum prothrombin conversion accelerator,SPCA
2B
(L)
Factor VIIa (Light Chain)polymer556030.81UniProt (P08709)
Pfam (PF14670)
Homo sapiens (Human)Proconvertin,Serum prothrombin conversion accelerator,SPCA
3C
(H)
7-chloro-3,4-dihydroisoquinolin-1(2H)-onenon-polymer181.61Chemie (3Z8)
4D
(H)
CALCIUM IONnon-polymer40.11Chemie (CA)
5E, F, G
(H)
SULFATE IONnon-polymer96.13Chemie (SO4)
6H
(H)
GLYCEROLnon-polymer92.11Chemie (GOL)
7I, J
(H, L)
waterwater18.0143Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34134.1
Non-Polymers*Number of molecules6
Total formula weight602.0
All*Total formula weight34736.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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