4X6Z
Yeast 20S proteasome in complex with PR-VI modulator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (1, M) | Proteasome subunit beta type-6 | polymer | 241 | 26905.1 | 2 | UniProt (P23724) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
| 2 | B, P (2, N) | Proteasome subunit beta type-7 | polymer | 266 | 29471.3 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 3 | C, Q (A, O) | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 4 | D, R (B, P) | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 5 | E, S (C, Q) | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 6 | F, T (D, R) | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF00227) Pfam (PF10584) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 7 | G, U (E, S) | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 8 | H, V (F, T) | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 9 | I, W (G, U) | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 10 | J, X (H, V) | Proteasome subunit beta type-1 | polymer | 215 | 23573.6 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 11 | K, Y (I, W) | Proteasome subunit beta type-2 | polymer | 261 | 28299.9 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
| 12 | L, Z (J, X) | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
| 13 | AA, M (K, Y) | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
| 14 | BA, N (L, Z) | Proteasome subunit beta type-5 | polymer | 287 | 31670.5 | 2 | UniProt (P30656) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
| 15 | CA, DA (a, e) | synthetic peptide (polymer) | polymer | 13 | 1673.0 | 2 | synthetic construct | ||
| 16 | DC, DD, EA, HD, IA... (M, T, 1, V, 2...) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 9 | Chemie (MPD) | |||
| 17 | AB, AC, AD, AE, BB... (F, L, S, Z, M...) | GLYCEROL | non-polymer | 92.1 | 38 | Chemie (GOL) | |||
| 18 | BC, BD, BE, CC, CD... (L, S, Z, F, T...) | MAGNESIUM ION | non-polymer | 24.3 | 56 | Chemie (MG) | |||
| 19 | AF, BF, CF, DE, DF... (V, W, X, 1, Y...) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 770154.1 | |
| Non-Polymers* | Number of molecules | 103 |
| Total formula weight | 5924.2 | |
| All* | Total formula weight | 776078.4 |
