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4X67

Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1733191821.61UniProt (P04050)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
2B
(B)
DNA-directed RNA polymerase II subunit RPB2polymer1224138937.31UniProt (P08518)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerase II subunit 2,B150,DNA-directed RNA polymerase II 140 kDa polypeptide,RNA polymerase II subunit 2,B150,DNA-directed RNA polymerase II 140 kDa polypeptide
3C
(C)
DNA-directed RNA polymerase II subunit RPB3polymer31835330.51UniProt (P16370)
Pfam (PF01193)
Pfam (PF01000)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerase II subunit B3,B44.5,DNA-directed RNA polymerase II 45 kDa polypeptide
4D
(E)
DNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21525117.11UniProt (P20434)
Pfam (PF03871)
Pfam (PF01191)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC1,ABC27,DNA-directed RNA polymerases I,and III 27 kDa polypeptide
5E
(F)
DNA-directed RNA polymerases I, II, and III subunit RPABC2polymer15517931.81UniProt (P20435)
Pfam (PF01192)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC2,ABC23,DNA-directed RNA polymerases I,and III 23 kDa polypeptide
6F
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14616525.41UniProt (P20436)
Pfam (PF03870)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC3,ABC14.4,ABC14.5,DNA-directed RNA polymerases I,and III 14.5 kDa polypeptide
7G
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12214308.21UniProt (P27999)
Pfam (PF02150)
Pfam (PF01096)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerase II subunit B9,B12.6,DNA-directed RNA polymerase II 14.2 kDa polypeptide,DNA-directed RNA polymerase II subunit 9
8H
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer708290.71UniProt (P22139)
Pfam (PF01194)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC5,ABC10-beta,ABC8,DNA-directed RNA polymerases I,and III 8.3 kDa polypeptide
9I
(K)
DNA-directed RNA polymerase II subunit RPB11polymer12013633.51UniProt (P38902)
Pfam (PF13656)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerase II subunit B11,B13.6,DNA-directed RNA polymerase II 13.6 kDa polypeptide
10J
(L)
DNA-directed RNA polymerases I, II, and III subunit RPABC4polymer707730.01UniProt (P40422)
Pfam (PF03604)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC4,ABC10-alpha
11K
(R)
RNA_9 merpolymer92879.81synthetic construct
12L
(T)
Template DNA _29 merpolymer298950.81synthetic construct
13M, N, O, P, Q...
(A, B, C, I, J...)
ZINC IONnon-polymer65.48Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight481456.5
Non-Polymers*Number of molecules8
Total formula weight523.3
All*Total formula weight481979.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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