4X5F
ecDHFR complexed with folate and NADP+ at 0.1 MPa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 162 | 18301.6 | 2 | UniProt (P0ABQ4) Pfam (PF00186) | Escherichia coli K12 | |
| 2 | C, F (A, B) | FOLIC ACID | non-polymer | 441.4 | 2 | Chemie (FOL) | |||
| 3 | D, G (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | E, H (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: P0ABQ4)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36603.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2525.9 | |
| All* | Total formula weight | 39129.1 |
