4X5D

Anthranilate phosphoribosyltransferase variant R193A from Mycobacterium tuberculosis with anthranilate bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Anthranilate phosphoribosyltransferase	polymer	378	38762.8	2	UniProt (A5U4M0) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5)	Mycobacterium tuberculosis
2	C, F (A, B)	2-AMINOBENZOIC ACID	non-polymer		137.1	2	Chemie (BE2)
3	D (A)	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
4	E, G (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	H, I (A, B)	water	water		18.0	235	Chemie (HOH)

Sequence modifications

A, B: 1 - 370 (UniProt: A5U4M0)

PDB	External Database	Details
Ala 193	Arg 193	engineered mutation
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77525.5
Non-Polymers*	Number of molecules	5
	Total formula weight	527.5
All*	Total formula weight	78053.1

*Water molecules are not included.