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4X3V

Crystal structure of human ribonucleotide reductase 1 bound to inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BRibonucleoside-diphosphate reductase large subunitpolymer79290179.02UniProt (P23921)
Pfam (PF03477)
Pfam (PF00317)
Pfam (PF02867)
In PDB
Homo sapiens (Human)Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large subunit
2A, BTHYMIDINE-5'-TRIPHOSPHATEnon-polymer482.22Chemie (TTP)
3AN~6~-{N-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]-2-methyl-D-alanyl}-D-lysinenon-polymer418.41Chemie (3X4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight180358.0
Non-Polymers*Number of molecules3
Total formula weight1382.8
All*Total formula weight181740.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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