4X3V
Crystal structure of human ribonucleotide reductase 1 bound to inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonucleoside-diphosphate reductase large subunit | polymer | 792 | 90179.0 | 2 | UniProt (P23921) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Homo sapiens (Human) | Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large subunit |
| 2 | C, E (A, B) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 2 | Chemie (TTP) | |||
| 3 | D (A) | N~6~-{N-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]-2-methyl-D-alanyl}-D-lysine | non-polymer | 418.4 | 1 | Chemie (3X4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 180358.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1382.8 | |
| All* | Total formula weight | 181740.8 |
