4WW2

Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	TCR Alpha Chain-TRAV21-TRAJ8	polymer	207	22574.0	1	Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (A0A0B4J279) UniProt (by SIFTS) (P01848) In PDB	Homo sapiens
2	B	TCR Beta Chain-TRBV7-8	polymer	243	27368.4	1	Pfam (PF07654) UniProt (by SIFTS) (A0A5B9) In PDB	Homo sapiens
3	C	Antigen-presenting glycoprotein CD1d	polymer	284	32324.4	1	UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (Human)	R3G1
4	F	Beta-2-microglobulin	polymer	99	11748.2	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
5	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	C	(15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide	non-polymer		828.3	1	Chemie (JLS)
7		water	water		18.0	170	Chemie (HOH)

Sequence modifications

C: 3 - 277 (UniProt: P15813)

PDB	External Database	Details
Ser 0	-	expression tag
Pro 1	-	expression tag
Gly 2	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94014.9
Non-Polymers*	Number of molecules	3
	Total formula weight	1270.7
All*	Total formula weight	95285.6

*Water molecules are not included.