4WW2
Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TCR Alpha Chain-TRAV21-TRAJ8 | polymer | 207 | 22574.0 | 1 | Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (A0A0B4J279) UniProt (by SIFTS) (P01848) | Homo sapiens | |
| 2 | B (B) | TCR Beta Chain-TRBV7-8 | polymer | 243 | 27368.4 | 1 | Pfam (PF07654) UniProt (by SIFTS) (A0A5B9) | Homo sapiens | |
| 3 | C (C) | Antigen-presenting glycoprotein CD1d | polymer | 284 | 32324.4 | 1 | UniProt (P15813) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (Human) | R3G1 |
| 4 | D (F) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 5 | E, F (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | G (C) | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide | non-polymer | 828.3 | 1 | Chemie (JLS) | |||
| 7 | H, I, J, K (A, B, C, F) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
C: 3 - 277 (UniProt: P15813)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Pro 1 | - | expression tag |
| Gly 2 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94014.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1270.7 | |
| All* | Total formula weight | 95285.6 |
