4WVP
Crystal structure of an activity-based probe HNE complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Neutrophil elastase | polymer | 218 | 23319.0 | 1 | UniProt (P08246) Pfam (PF00089) | Homo sapiens (Human) | Bone marrow serine protease,Elastase-2,Human leukocyte elastase,HLE,Medullasin,PMN elastase |
| 2 | B (I) | BTN-3V3-NLB-OMT-OIC-3V2 | polymer | 6 | 1146.4 | 1 | BIRD (PRD_002139) | synthetic construct | |
| 3 | C (A) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 5 | E, F, M (E, I) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | G, H, I, J, K... (E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | N, O (E, I) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24465.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1303.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 660.6 | |
| All* | Total formula weight | 26429.2 |
