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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4WOI

4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AA, DA16S ribosomal RNApolymer1542499690.02GenBank (359330873)Escherichia coli str. K-12 substr. MDS42
2AB, DB30S ribosomal protein S2polymer24126781.72UniProt (P0A7V0)
Pfam (PF00318)
In PDB		Escherichia coli
3AC, DC30S ribosomal protein S3polymer23326031.32UniProt (P0A7V3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Escherichia coli
4AD, DD30S ribosomal protein S4polymer20623514.22UniProt (P0A7V8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Escherichia coli
5AE, DE30S ribosomal protein S5polymer16717629.42UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Escherichia coli
6AF, DF30S ribosomal protein S6polymer13515727.52UniProt (P02358)
Pfam (PF01250)
In PDB		Escherichia coli
7AG, DG30S ribosomal protein S7polymer17920055.22UniProt (P02359)
Pfam (PF00177)
In PDB		Escherichia coli
8AH, DH30S ribosomal protein S8polymer13014146.62UniProt (P0A7W7)
Pfam (PF00410)
In PDB		Escherichia coli
9AI, DI30S ribosomal protein S9polymer13014886.32UniProt (P0A7X3)
Pfam (PF00380)
In PDB		Escherichia coli
10AJ, DJ30S ribosomal protein S10polymer10311755.62UniProt (P0A7R5)
Pfam (PF00338)
In PDB		Escherichia coli
11AK, DK30S ribosomal protein S11polymer12913871.02UniProt (P0A7R9)
Pfam (PF00411)
In PDB		Escherichia coli
12AL, DL30S ribosomal protein S12polymer12413768.22UniProt (P0A7S3)
Pfam (PF00164)
In PDB		Escherichia coli
13AM, DM30S ribosomal protein S13polymer11813128.52UniProt (P0A7S9)
Pfam (PF00416)
In PDB		Escherichia coli
14AN, DN30S ribosomal protein S14polymer10111606.62UniProt (P0AG59)
Pfam (PF00253)
In PDB		Escherichia coli
15AO, DO30S ribosomal protein S15polymer8910319.92UniProt (C6UUI7)
In PDB		Escherichia coli
16AP, DP30S ribosomal protein S16polymer829207.62UniProt (P0A7T3)
Pfam (PF00886)
In PDB		Escherichia coli
17AQ, DQ30S ribosomal protein S17polymer849724.52UniProt (P0AG63)
Pfam (PF00366)
In PDB		Escherichia coli
18AR, DR30S ribosomal protein S18polymer759005.52UniProt (P0A7T7)
Pfam (PF01084)
In PDB		Escherichia coli
19AS, DS30S ribosomal protein S19polymer9210455.42UniProt (P0A7U3)
Pfam (PF00203)
In PDB		Escherichia coli
20AT, DT30S ribosomal protein S20polymer879708.52UniProt (P0A7U7)
Pfam (PF01649)
In PDB		Escherichia coli
21AU, DU30S ribosomal protein S21polymer718524.02UniProt (P68679)
Pfam (PF01165)
In PDB		Escherichia coli
22AVRibosome-recycling factorpolymer18520671.61UniProt (P0A805)
Pfam (PF01765)
In PDB		Escherichia coliRRF,Ribosome-releasing factor
23AW, DVMessenger RNApolymer165170.22Enterobacteria phage L1
24AX, DWPhenylalanine specific transfer RNA, tRNA-Phepolymer7624485.52GenBank (359330873)Escherichia coli str. K-12 substr. MDS42
25BA, CA23S ribosomal RNApolymer2904941612.42GenBank (359330873)Escherichia coli str. K-12 substr. MDS42
26BB, CB5S ribosomal RNApolymer12038790.12GenBank (359330873)Escherichia coli str. K-12 substr. MDS42
27BC, CC50S ribosomal protein L2polymer27329923.62UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Escherichia coli
28BD, CD50S ribosomal protein L3polymer20922277.52UniProt (P60438)
Pfam (PF00297)
In PDB		Escherichia coli
29BE, CE50S ribosomal protein L4polymer20122121.62UniProt (P60723)
Pfam (PF00573)
In PDB		Escherichia coli
30BF, CF50S ribosomal protein L5polymer17920333.62UniProt (P62399)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Escherichia coli
31BG, CG50S ribosomal protein L6polymer17718932.82UniProt (P0AG55)
Pfam (PF00347)
In PDB		Escherichia coli
32BH, CH50S ribosomal protein L9polymer14915789.02UniProt (P0A7R1)
Pfam (PF01281)
Pfam (PF03948)
In PDB		Escherichia coli
33BI, CI50S ribosomal protein L11polymer14214894.42UniProt (P0A7J7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Escherichia coli
34BJ, CJ50S ribosomal protein L13polymer14216050.62UniProt (P0AA10)
Pfam (PF00572)
In PDB		Escherichia coli
35BK, CK50S ribosomal protein L14polymer12313565.12UniProt (P0ADY3)
Pfam (PF00238)
In PDB		Escherichia coli
36BL, CL50S ribosomal protein L15polymer14415008.52UniProt (P02413)
Pfam (PF00828)
In PDB		Escherichia coli
37BM, CM50S ribosomal protein L16polymer13615312.32UniProt (P0ADY7)
Pfam (PF00252)
In PDB		Escherichia coli
38BN, CN50S ribosomal protein L17polymer12714393.72UniProt (P0AG44)
Pfam (PF01196)
In PDB		Escherichia coli
39BO, CO50S ribosomal protein L18polymer11712794.72UniProt (P0C018)
Pfam (PF00861)
In PDB		Escherichia coli
40BP, CP50S ribosomal protein L19polymer11513159.32UniProt (P0A7K6)
Pfam (PF01245)
In PDB		Escherichia coli
41BQ, CQ50S ribosomal protein L20polymer11813528.02UniProt (P0A7L3)
Pfam (PF00453)
In PDB		Escherichia coli
42BR, CR50S ribosomal protein L21polymer10311586.42UniProt (P0AG48)
Pfam (PF00829)
In PDB		Escherichia coli
43BS, CS50S ribosomal protein L22polymer11012253.42UniProt (P61175)
Pfam (PF00237)
In PDB		Escherichia coli
44BT, CT50S ribosomal protein L23polymer10011222.22UniProt (P0ADZ0)
Pfam (PF00276)
In PDB		Escherichia coli
45BU, CU50S ribosomal protein L24polymer10411339.32UniProt (P60624)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Escherichia coli
46BV, CV50S ribosomal protein L25polymer9410713.52UniProt (P68919)
Pfam (PF01386)
In PDB		Escherichia coli
47BW, CW50S ribosomal protein L27polymer859146.52UniProt (P0A7L8)
Pfam (PF01016)
In PDB		Escherichia coli
48BX, CX50S ribosomal protein L28polymer789027.62UniProt (P0A7M2)
Pfam (PF00830)
In PDB		Escherichia coli
49BY, CY50S ribosomal protein L29polymer637286.52UniProt (P0A7M6)
Pfam (PF00831)
In PDB		Escherichia coli
50BZ, CZ50S ribosomal protein L30polymer596554.82UniProt (P0AG51)
Pfam (PF00327)
In PDB		Escherichia coli
51B0, C050S ribosomal protein L32polymer576463.42UniProt (P0A7N4)
Pfam (PF01783)
In PDB		Escherichia coli
52B1, C150S ribosomal protein L33polymer556388.62UniProt (P0A7N9)
Pfam (PF00471)
In PDB		Escherichia coli
53B2, C250S ribosomal protein L34polymer465397.52UniProt (P0A7P5)
Pfam (PF00468)
In PDB		Escherichia coli
54B3, C350S ribosomal protein L35polymer657313.02UniProt (P0A7Q1)
Pfam (PF01632)
In PDB		Escherichia coliRibosomal protein A
55B4, C450S ribosomal protein L36polymer384377.42UniProt (P0A7Q6)
Pfam (PF00444)
In PDB		Escherichia coliRibosomal protein B
56B550S ribosomal protein L1polymer22824741.51UniProt (Q5SLP7)
Pfam (PF00687)
In PDB		Thermus thermophilus
57AA, AN, BA, CA, DA...MAGNESIUM IONnon-polymer24.3495Chemie (MG)
58BA, CA, DA, AAPAROMOMYCINnon-polymer615.613Chemie (PAR)
59C4, B4ZINC IONnon-polymer65.42Chemie (ZN)
60waterwater18.01727Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains110
Total formula weight4398912.7
Non-Polymers*Number of molecules510
Total formula weight20165.0
All*Total formula weight4419077.7
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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