4WNK

Crystal Structure of Bovine G Protein Coupled-Receptor Kinase 5 in Complex with CCG215022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	G protein-coupled receptor kinase 5	polymer	598	69037.9	1	UniProt (P43249) Pfam (PF00615) Pfam (PF00069) In PDB	Bos taurus (Bovine)	G protein-coupled receptor kinase GRK5
2	A	(4S)-4-{4-fluoro-3-[(pyridin-2-ylmethyl)carbamoyl]phenyl}-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide	non-polymer		499.5	1	Chemie (453)
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	37	Chemie (HOH)

Sequence modifications

A: 1 - 624 (UniProt: P43249)

PDB	External Database	Details
Val 625	-	expression tag
Asp 626	-	expression tag
His 627	-	expression tag
His 628	-	expression tag
His 629	-	expression tag
His 630	-	expression tag
His 631	-	expression tag
His 632	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	69037.9
Non-Polymers*	Number of molecules	2
	Total formula weight	595.6
All*	Total formula weight	69633.4

*Water molecules are not included.