4WNK
Crystal Structure of Bovine G Protein Coupled-Receptor Kinase 5 in Complex with CCG215022
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G protein-coupled receptor kinase 5 | polymer | 598 | 69037.9 | 1 | UniProt (P43249) Pfam (PF00615) Pfam (PF00069) | Bos taurus (Bovine) | G protein-coupled receptor kinase GRK5 |
| 2 | B (A) | (4S)-4-{4-fluoro-3-[(pyridin-2-ylmethyl)carbamoyl]phenyl}-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide | non-polymer | 499.5 | 1 | Chemie (453) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 1 - 624 (UniProt: P43249)
| PDB | External Database | Details |
|---|---|---|
| Val 625 | - | expression tag |
| Asp 626 | - | expression tag |
| His 627 | - | expression tag |
| His 628 | - | expression tag |
| His 629 | - | expression tag |
| His 630 | - | expression tag |
| His 631 | - | expression tag |
| His 632 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69037.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 595.6 | |
| All* | Total formula weight | 69633.4 |
