Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0004703 | molecular_function | G protein-coupled receptor kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005886 | cellular_component | plasma membrane |
A | 0006468 | biological_process | protein phosphorylation |
A | 0006915 | biological_process | apoptotic process |
A | 0007165 | biological_process | signal transduction |
A | 0008289 | molecular_function | lipid binding |
A | 0009966 | biological_process | regulation of signal transduction |
A | 0016055 | biological_process | Wnt signaling pathway |
A | 0043066 | biological_process | negative regulation of apoptotic process |
A | 0046777 | biological_process | protein autophosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | binding site for residue 453 A 701 |
Chain | Residue |
A | LEU192 |
A | LYS215 |
A | LEU217 |
A | MET230 |
A | GLU234 |
A | THR264 |
A | ILE265 |
A | MET266 |
A | GLU315 |
A | ASN316 |
A | LEU318 |
A | GLY193 |
A | SER328 |
A | ASP329 |
A | HOH804 |
A | HOH817 |
A | LYS194 |
A | GLY195 |
A | GLY196 |
A | PHE197 |
A | GLY198 |
A | VAL200 |
A | ALA213 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 702 |
Chain | Residue |
A | LYS183 |
A | THR255 |
A | LYS256 |
A | HOH837 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 33 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGGFGEVCaCqvratgkmyackrlekk.RIKK |
Chain | Residue | Details |
A | LEU192-LYS224 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvYrDLKpeNILL |
Chain | Residue | Details |
A | ILE307-LEU319 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP311 | |
Chain | Residue | Details |
A | LEU192 | |
A | LYS215 | |
Chain | Residue | Details |
A | SER484 | |
Chain | Residue | Details |
A | THR485 | |
Chain | Residue | Details |
A | SER613 | |