4WND
Crystal structure of the TPR domain of LGN in complex with Frmpd4/Preso1 at 1.5 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G-protein-signaling modulator 2 | polymer | 406 | 44948.3 | 1 | UniProt (P81274) Pfam (PF13374) Pfam (PF13176) Pfam (PF13181) | Homo sapiens (Human) | Mosaic protein LGN |
| 2 | B (B) | FERM and PDZ domain-containing protein 4 | polymer | 53 | 5831.6 | 1 | UniProt (Q14CM0) | Homo sapiens (Human) | PDZ domain-containing protein 10,PSD-95-interacting regulator of spine morphogenesis,Preso |
| 3 | C, D, E, F, G... (A) | THIOCYANATE ION | non-polymer | 58.1 | 7 | Chemie (SCN) | |||
| 4 | J, K, L, M, N (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 5 | O (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | P, Q, R, S, T... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | V, W (A, B) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 13 - 414 (UniProt: P81274)
B: 978 - 1025 (UniProt: Q14CM0)
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Ser 12 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 973 | - | expression tag |
| Pro 974 | - | expression tag |
| Leu 975 | - | expression tag |
| Gly 976 | - | expression tag |
| Ser 977 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50779.9 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1459.8 | |
| All* | Total formula weight | 52239.7 |
