4WND

Crystal structure of the TPR domain of LGN in complex with Frmpd4/Preso1 at 1.5 Angstrom resolution

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SCN A 501

Chain	Residue
A	LEU82
A	SER98
A	HOH628

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SCN A 502

Chain	Residue
A	GLY109
A	ASN110
A	GLU113

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SCN A 503

Chain	Residue
A	PGE513
A	HOH608
A	GLU179
A	PHE198
A	LEU201

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SCN A 504

Chain	Residue
A	LYS231
A	ALA232
A	ARG235
A	LEU268
A	HOH669

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SCN A 505

Chain	Residue
A	ARG266
A	LEU268
A	ARG271
A	GLU274
A	HOH746

---

site_id	AC6
Number of Residues	3
Details	binding site for residue SCN A 506

Chain	Residue
A	GLN119
A	ARG126
A	HOH771

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SCN A 507

Chain	Residue
A	GLU25
A	ARG26
A	HOH647

---

site_id	AC8
Number of Residues	6
Details	binding site for residue PEG A 508

Chain	Residue
A	LYS106
A	ASN143
A	HIS146
A	LYS150
A	HOH768
B	GLU1000

---

site_id	AC9
Number of Residues	2
Details	binding site for residue PEG A 509

Chain	Residue
A	SER151
A	PHE152

---

site_id	AD1
Number of Residues	2
Details	binding site for residue PEG A 510

Chain	Residue
A	HIS341
B	LEU990

---

site_id	AD2
Number of Residues	7
Details	binding site for residue PEG A 511

Chain	Residue
A	TYR145
A	LYS148
A	ASP169
A	ALA170
A	HOH606
A	HOH744
A	HOH749

---

site_id	AD3
Number of Residues	7
Details	binding site for residue PEG A 512

Chain	Residue
A	ALA275
A	GLN276
A	TYR279
A	HIS301
A	ASP310
A	ARG316
A	HOH802

---

site_id	AD4
Number of Residues	12
Details	binding site for residue PGE A 513

Chain	Residue
A	ARG34
A	ALA35
A	SER38
A	PHE39
A	THR186
A	GLN194
A	PHE198
A	GLN220
A	SCN503
A	HOH619
A	HOH645
A	HOH678

---

site_id	AD5
Number of Residues	4
Details	binding site for residue EDO A 514

Chain	Residue
A	TYR206
A	LEU207
A	PHE211
A	PHE247

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO A 515

Chain	Residue
A	HIS79
A	HIS80
A	THR83
A	HOH620
A	HOH735

---

site_id	AD7
Number of Residues	2
Details	binding site for residue EDO A 516

Chain	Residue
A	GLU256
A	LYS260

---

site_id	AD8
Number of Residues	3
Details	binding site for residue EDO A 517

Chain	Residue
A	LYS148
A	PHE152
A	HOH749

---

site_id	AD9
Number of Residues	4
Details	binding site for residue EDO A 518

Chain	Residue
A	GLN289
A	ASP290
A	TYR291
A	GLU292

---

site_id	AE1
Number of Residues	5
Details	binding site for residue EDO A 519

Chain	Residue
A	GLU113
A	VAL116
A	CYS117
A	HOH615
A	HOH628

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	33
Details	Repeat: {"description":"TPR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	33
Details	Repeat: {"description":"TPR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	33
Details	Repeat: {"description":"TPR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	33
Details	Repeat: {"description":"TPR 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	33
Details	Repeat: {"description":"TPR 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	33
Details	Repeat: {"description":"TPR 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	33
Details	Repeat: {"description":"TPR 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PKG","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---