4WJG
Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K, P, U... (A, F, K, P, U...) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 6 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | AA, B, G, L, Q... (B, G, L, Q, V...) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 6 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | BA, C, H, M, R... (C, H, M, R, W...) | Haptoglobin | polymer | 315 | 35267.1 | 6 | UniProt (P00738) Pfam (PF00089) | Homo sapiens (Human) | Zonulin |
| 4 | CA, D, I, N, S... (D, I, N, S, X...) | Iron-regulated surface determinant protein H | polymer | 146 | 16877.6 | 6 | UniProt (Q99TD3) Pfam (PF05031) | Staphylococcus aureus subsp. aureus N315 | Haptoglobin receptor A,Staphylococcus aureus surface protein I |
| 5 | DA, E, J, O, T... (E, J, O, T, Y...) | Haptoglobin-hemoglobin receptor | polymer | 343 | 36848.6 | 6 | UniProt (I7BA80) Pfam (PF20933) | Trypanosoma brucei brucei | |
| 6 | EA, FA, GA, HA, IA... (a, b, c, d, e...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | Trypanosoma brucei brucei | ||
| 7 | CC, EB, EC, GB, MB... (Z, K, 1, L, P...) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 12 | Chemie (HEM) | Homo sapiens (Human) | ||
| 8 | DC, FB, FC, HB, NB... (Z, K, 1, L, P...) | OXYGEN MOLECULE | non-polymer | 32.0 | 12 | Chemie (OXY) | Homo sapiens (Human) | ||
| 9 | AB, AC, BB, BC, CB... (H, Y, J, 2, 4...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 23 | Chemie (NAG) | Trypanosoma brucei brucei |
Sequence modifications
D, I, N, S, X, 3: 86 - 229 (UniProt: Q99TD3)
| PDB | External Database | Details |
|---|---|---|
| Gly 84 | - | expression tag |
| Ser 85 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 720203.1 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 4244.0 | |
| Non-Polymers* | Number of molecules | 47 |
| Total formula weight | 12869.6 | |
| All* | Total formula weight | 737316.7 |
