4WJG

Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0004601	molecular_function	peroxidase activity
1	0005344	molecular_function	oxygen carrier activity
1	0005515	molecular_function	protein binding
1	0005576	cellular_component	extracellular region
1	0005615	cellular_component	extracellular space
1	0005829	cellular_component	cytosol
1	0005833	cellular_component	hemoglobin complex
1	0006954	biological_process	inflammatory response
1	0008217	biological_process	regulation of blood pressure
1	0015670	biological_process	carbon dioxide transport
1	0015671	biological_process	oxygen transport
1	0019825	molecular_function	oxygen binding
1	0020037	molecular_function	heme binding
1	0030185	biological_process	nitric oxide transport
1	0030492	molecular_function	hemoglobin binding
1	0031720	molecular_function	haptoglobin binding
1	0031721	molecular_function	hemoglobin alpha binding
1	0031838	cellular_component	haptoglobin-hemoglobin complex
1	0042542	biological_process	response to hydrogen peroxide
1	0042744	biological_process	hydrogen peroxide catabolic process
1	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
1	0046872	molecular_function	metal ion binding
1	0048821	biological_process	erythrocyte development
1	0070062	cellular_component	extracellular exosome
1	0070293	biological_process	renal absorption
1	0070527	biological_process	platelet aggregation
1	0071682	cellular_component	endocytic vesicle lumen
1	0072562	cellular_component	blood microparticle
1	0097746	biological_process	blood vessel diameter maintenance
1	0098869	biological_process	cellular oxidant detoxification
1	1904724	cellular_component	tertiary granule lumen
1	1904813	cellular_component	ficolin-1-rich granule lumen
2	0004252	molecular_function	serine-type endopeptidase activity
2	0005576	cellular_component	extracellular region
2	0006508	biological_process	proteolysis
2	0030492	molecular_function	hemoglobin binding
4	0046872	molecular_function	metal ion binding
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005829	cellular_component	cytosol
A	0005833	cellular_component	hemoglobin complex
A	0006954	biological_process	inflammatory response
A	0015670	biological_process	carbon dioxide transport
A	0015671	biological_process	oxygen transport
A	0016020	cellular_component	membrane
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0030185	biological_process	nitric oxide transport
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042542	biological_process	response to hydrogen peroxide
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0046872	molecular_function	metal ion binding
A	0048821	biological_process	erythrocyte development
A	0070062	cellular_component	extracellular exosome
A	0071682	cellular_component	endocytic vesicle lumen
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005829	cellular_component	cytosol
B	0005833	cellular_component	hemoglobin complex
B	0006954	biological_process	inflammatory response
B	0008217	biological_process	regulation of blood pressure
B	0015670	biological_process	carbon dioxide transport
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0030185	biological_process	nitric oxide transport
B	0030492	molecular_function	hemoglobin binding
B	0031720	molecular_function	haptoglobin binding
B	0031721	molecular_function	hemoglobin alpha binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042542	biological_process	response to hydrogen peroxide
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0048821	biological_process	erythrocyte development
B	0070062	cellular_component	extracellular exosome
B	0070293	biological_process	renal absorption
B	0070527	biological_process	platelet aggregation
B	0071682	cellular_component	endocytic vesicle lumen
B	0072562	cellular_component	blood microparticle
B	0097746	biological_process	blood vessel diameter maintenance
B	0098869	biological_process	cellular oxidant detoxification
B	1904724	cellular_component	tertiary granule lumen
B	1904813	cellular_component	ficolin-1-rich granule lumen
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005576	cellular_component	extracellular region
C	0006508	biological_process	proteolysis
C	0030492	molecular_function	hemoglobin binding
E	0046872	molecular_function	metal ion binding
F	0004601	molecular_function	peroxidase activity
F	0005344	molecular_function	oxygen carrier activity
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005829	cellular_component	cytosol
F	0005833	cellular_component	hemoglobin complex
F	0006954	biological_process	inflammatory response
F	0015670	biological_process	carbon dioxide transport
F	0015671	biological_process	oxygen transport
F	0016020	cellular_component	membrane
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
F	0030185	biological_process	nitric oxide transport
F	0031720	molecular_function	haptoglobin binding
F	0031838	cellular_component	haptoglobin-hemoglobin complex
F	0042542	biological_process	response to hydrogen peroxide
F	0042744	biological_process	hydrogen peroxide catabolic process
F	0046872	molecular_function	metal ion binding
F	0048821	biological_process	erythrocyte development
F	0070062	cellular_component	extracellular exosome
F	0071682	cellular_component	endocytic vesicle lumen
F	0072562	cellular_component	blood microparticle
F	0098869	biological_process	cellular oxidant detoxification
G	0004601	molecular_function	peroxidase activity
G	0005344	molecular_function	oxygen carrier activity
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0005829	cellular_component	cytosol
G	0005833	cellular_component	hemoglobin complex
G	0006954	biological_process	inflammatory response
G	0008217	biological_process	regulation of blood pressure
G	0015670	biological_process	carbon dioxide transport
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0030185	biological_process	nitric oxide transport
G	0030492	molecular_function	hemoglobin binding
G	0031720	molecular_function	haptoglobin binding
G	0031721	molecular_function	hemoglobin alpha binding
G	0031838	cellular_component	haptoglobin-hemoglobin complex
G	0042542	biological_process	response to hydrogen peroxide
G	0042744	biological_process	hydrogen peroxide catabolic process
G	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
G	0046872	molecular_function	metal ion binding
G	0048821	biological_process	erythrocyte development
G	0070062	cellular_component	extracellular exosome
G	0070293	biological_process	renal absorption
G	0070527	biological_process	platelet aggregation
G	0071682	cellular_component	endocytic vesicle lumen
G	0072562	cellular_component	blood microparticle
G	0097746	biological_process	blood vessel diameter maintenance
G	0098869	biological_process	cellular oxidant detoxification
G	1904724	cellular_component	tertiary granule lumen
G	1904813	cellular_component	ficolin-1-rich granule lumen
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005576	cellular_component	extracellular region
H	0006508	biological_process	proteolysis
H	0030492	molecular_function	hemoglobin binding
J	0046872	molecular_function	metal ion binding
K	0004601	molecular_function	peroxidase activity
K	0005344	molecular_function	oxygen carrier activity
K	0005506	molecular_function	iron ion binding
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0005829	cellular_component	cytosol
K	0005833	cellular_component	hemoglobin complex
K	0006954	biological_process	inflammatory response
K	0015670	biological_process	carbon dioxide transport
K	0015671	biological_process	oxygen transport
K	0016020	cellular_component	membrane
K	0019825	molecular_function	oxygen binding
K	0020037	molecular_function	heme binding
K	0030185	biological_process	nitric oxide transport
K	0031720	molecular_function	haptoglobin binding
K	0031838	cellular_component	haptoglobin-hemoglobin complex
K	0042542	biological_process	response to hydrogen peroxide
K	0042744	biological_process	hydrogen peroxide catabolic process
K	0046872	molecular_function	metal ion binding
K	0048821	biological_process	erythrocyte development
K	0070062	cellular_component	extracellular exosome
K	0071682	cellular_component	endocytic vesicle lumen
K	0072562	cellular_component	blood microparticle
K	0098869	biological_process	cellular oxidant detoxification
L	0004601	molecular_function	peroxidase activity
L	0005344	molecular_function	oxygen carrier activity
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005829	cellular_component	cytosol
L	0005833	cellular_component	hemoglobin complex
L	0006954	biological_process	inflammatory response
L	0008217	biological_process	regulation of blood pressure
L	0015670	biological_process	carbon dioxide transport
L	0015671	biological_process	oxygen transport
L	0019825	molecular_function	oxygen binding
L	0020037	molecular_function	heme binding
L	0030185	biological_process	nitric oxide transport
L	0030492	molecular_function	hemoglobin binding
L	0031720	molecular_function	haptoglobin binding
L	0031721	molecular_function	hemoglobin alpha binding
L	0031838	cellular_component	haptoglobin-hemoglobin complex
L	0042542	biological_process	response to hydrogen peroxide
L	0042744	biological_process	hydrogen peroxide catabolic process
L	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
L	0046872	molecular_function	metal ion binding
L	0048821	biological_process	erythrocyte development
L	0070062	cellular_component	extracellular exosome
L	0070293	biological_process	renal absorption
L	0070527	biological_process	platelet aggregation
L	0071682	cellular_component	endocytic vesicle lumen
L	0072562	cellular_component	blood microparticle
L	0097746	biological_process	blood vessel diameter maintenance
L	0098869	biological_process	cellular oxidant detoxification
L	1904724	cellular_component	tertiary granule lumen
L	1904813	cellular_component	ficolin-1-rich granule lumen
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005576	cellular_component	extracellular region
M	0006508	biological_process	proteolysis
M	0030492	molecular_function	hemoglobin binding
O	0046872	molecular_function	metal ion binding
P	0004601	molecular_function	peroxidase activity
P	0005344	molecular_function	oxygen carrier activity
P	0005506	molecular_function	iron ion binding
P	0005515	molecular_function	protein binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0005829	cellular_component	cytosol
P	0005833	cellular_component	hemoglobin complex
P	0006954	biological_process	inflammatory response
P	0015670	biological_process	carbon dioxide transport
P	0015671	biological_process	oxygen transport
P	0016020	cellular_component	membrane
P	0019825	molecular_function	oxygen binding
P	0020037	molecular_function	heme binding
P	0030185	biological_process	nitric oxide transport
P	0031720	molecular_function	haptoglobin binding
P	0031838	cellular_component	haptoglobin-hemoglobin complex
P	0042542	biological_process	response to hydrogen peroxide
P	0042744	biological_process	hydrogen peroxide catabolic process
P	0046872	molecular_function	metal ion binding
P	0048821	biological_process	erythrocyte development
P	0070062	cellular_component	extracellular exosome
P	0071682	cellular_component	endocytic vesicle lumen
P	0072562	cellular_component	blood microparticle
P	0098869	biological_process	cellular oxidant detoxification
Q	0004601	molecular_function	peroxidase activity
Q	0005344	molecular_function	oxygen carrier activity
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005615	cellular_component	extracellular space
Q	0005829	cellular_component	cytosol
Q	0005833	cellular_component	hemoglobin complex
Q	0006954	biological_process	inflammatory response
Q	0008217	biological_process	regulation of blood pressure
Q	0015670	biological_process	carbon dioxide transport
Q	0015671	biological_process	oxygen transport
Q	0019825	molecular_function	oxygen binding
Q	0020037	molecular_function	heme binding
Q	0030185	biological_process	nitric oxide transport
Q	0030492	molecular_function	hemoglobin binding
Q	0031720	molecular_function	haptoglobin binding
Q	0031721	molecular_function	hemoglobin alpha binding
Q	0031838	cellular_component	haptoglobin-hemoglobin complex
Q	0042542	biological_process	response to hydrogen peroxide
Q	0042744	biological_process	hydrogen peroxide catabolic process
Q	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
Q	0046872	molecular_function	metal ion binding
Q	0048821	biological_process	erythrocyte development
Q	0070062	cellular_component	extracellular exosome
Q	0070293	biological_process	renal absorption
Q	0070527	biological_process	platelet aggregation
Q	0071682	cellular_component	endocytic vesicle lumen
Q	0072562	cellular_component	blood microparticle
Q	0097746	biological_process	blood vessel diameter maintenance
Q	0098869	biological_process	cellular oxidant detoxification
Q	1904724	cellular_component	tertiary granule lumen
Q	1904813	cellular_component	ficolin-1-rich granule lumen
R	0004252	molecular_function	serine-type endopeptidase activity
R	0005576	cellular_component	extracellular region
R	0006508	biological_process	proteolysis
R	0030492	molecular_function	hemoglobin binding
T	0046872	molecular_function	metal ion binding
U	0004601	molecular_function	peroxidase activity
U	0005344	molecular_function	oxygen carrier activity
U	0005506	molecular_function	iron ion binding
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005615	cellular_component	extracellular space
U	0005829	cellular_component	cytosol
U	0005833	cellular_component	hemoglobin complex
U	0006954	biological_process	inflammatory response
U	0015670	biological_process	carbon dioxide transport
U	0015671	biological_process	oxygen transport
U	0016020	cellular_component	membrane
U	0019825	molecular_function	oxygen binding
U	0020037	molecular_function	heme binding
U	0030185	biological_process	nitric oxide transport
U	0031720	molecular_function	haptoglobin binding
U	0031838	cellular_component	haptoglobin-hemoglobin complex
U	0042542	biological_process	response to hydrogen peroxide
U	0042744	biological_process	hydrogen peroxide catabolic process
U	0046872	molecular_function	metal ion binding
U	0048821	biological_process	erythrocyte development
U	0070062	cellular_component	extracellular exosome
U	0071682	cellular_component	endocytic vesicle lumen
U	0072562	cellular_component	blood microparticle
U	0098869	biological_process	cellular oxidant detoxification
V	0004601	molecular_function	peroxidase activity
V	0005344	molecular_function	oxygen carrier activity
V	0005515	molecular_function	protein binding
V	0005576	cellular_component	extracellular region
V	0005615	cellular_component	extracellular space
V	0005829	cellular_component	cytosol
V	0005833	cellular_component	hemoglobin complex
V	0006954	biological_process	inflammatory response
V	0008217	biological_process	regulation of blood pressure
V	0015670	biological_process	carbon dioxide transport
V	0015671	biological_process	oxygen transport
V	0019825	molecular_function	oxygen binding
V	0020037	molecular_function	heme binding
V	0030185	biological_process	nitric oxide transport
V	0030492	molecular_function	hemoglobin binding
V	0031720	molecular_function	haptoglobin binding
V	0031721	molecular_function	hemoglobin alpha binding
V	0031838	cellular_component	haptoglobin-hemoglobin complex
V	0042542	biological_process	response to hydrogen peroxide
V	0042744	biological_process	hydrogen peroxide catabolic process
V	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
V	0046872	molecular_function	metal ion binding
V	0048821	biological_process	erythrocyte development
V	0070062	cellular_component	extracellular exosome
V	0070293	biological_process	renal absorption
V	0070527	biological_process	platelet aggregation
V	0071682	cellular_component	endocytic vesicle lumen
V	0072562	cellular_component	blood microparticle
V	0097746	biological_process	blood vessel diameter maintenance
V	0098869	biological_process	cellular oxidant detoxification
V	1904724	cellular_component	tertiary granule lumen
V	1904813	cellular_component	ficolin-1-rich granule lumen
W	0004252	molecular_function	serine-type endopeptidase activity
W	0005576	cellular_component	extracellular region
W	0006508	biological_process	proteolysis
W	0030492	molecular_function	hemoglobin binding
Y	0046872	molecular_function	metal ion binding
Z	0004601	molecular_function	peroxidase activity
Z	0005344	molecular_function	oxygen carrier activity
Z	0005506	molecular_function	iron ion binding
Z	0005515	molecular_function	protein binding
Z	0005576	cellular_component	extracellular region
Z	0005615	cellular_component	extracellular space
Z	0005829	cellular_component	cytosol
Z	0005833	cellular_component	hemoglobin complex
Z	0006954	biological_process	inflammatory response
Z	0015670	biological_process	carbon dioxide transport
Z	0015671	biological_process	oxygen transport
Z	0016020	cellular_component	membrane
Z	0019825	molecular_function	oxygen binding
Z	0020037	molecular_function	heme binding
Z	0030185	biological_process	nitric oxide transport
Z	0031720	molecular_function	haptoglobin binding
Z	0031838	cellular_component	haptoglobin-hemoglobin complex
Z	0042542	biological_process	response to hydrogen peroxide
Z	0042744	biological_process	hydrogen peroxide catabolic process
Z	0046872	molecular_function	metal ion binding
Z	0048821	biological_process	erythrocyte development
Z	0070062	cellular_component	extracellular exosome
Z	0071682	cellular_component	endocytic vesicle lumen
Z	0072562	cellular_component	blood microparticle
Z	0098869	biological_process	cellular oxidant detoxification

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Peptide: {"description":"Hemopressin","featureId":"PRO_0000455882","evidences":[{"source":"PubMed","id":"18077343","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1704
Details	Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	198
Details	Site: {"description":"(Microbial infection) Cleavage; by N.americanus apr-2","evidences":[{"source":"PubMed","id":"12552433","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	48
Details	Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"7358733","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	30
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	18
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	24
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	18
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	24
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; alternate","evidences":[{"source":"PubMed","id":"7358733","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	30
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine","evidences":[{"source":"PubMed","id":"7358733","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	54
Details	Peptide: {"description":"LVV-hemorphin-7","featureId":"PRO_0000296641"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	36
Details	Peptide: {"description":"Spinorphin","featureId":"PRO_0000424226"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	24
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	6
Details	Binding site: {"description":"distal binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	6
Details	Binding site: {"description":"proximal binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	6
Details	Modified residue: {"description":"N-pyruvate 2-iminyl-valine; in Hb A1b"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"4531009","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	6
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"8637569","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9843411","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"4531009","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) valine; in Hb A1c","evidences":[{"source":"PubMed","id":"635569","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1452
Details	Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	30
Details	Region: {"description":"Interaction with CD163","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19838169","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---