4WEF
Structure of the Hemagglutinin-neuraminidase from Human parainfluenza virus type III: complex with difluorosialic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Hemagglutinin-neuraminidase glycoprotein | polymer | 431 | 48077.7 | 2 | UniProt (Q6WJ03) Pfam (PF00423) In PDB | Human parainfluenza virus 3 | |
2 | C, E | beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G31886NL) | |||
3 | D, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | A, B | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid | non-polymer | 327.3 | 2 | Chemie (FSI) | |||
6 | A, B | (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate | non-polymer | 309.2 | 2 | Chemie (DF4) | |||
7 | A, B | (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid | non-polymer | 329.3 | 3 | Chemie (SFJ) | |||
8 | B, A | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
9 | B, A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
10 | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A, B: 142 - 572 (UniProt: Q6WJ03)
PDB | External Database | Details |
---|---|---|
Gly 408 | Ser 408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96155.4 | |
Branched | Number of molecules | 4 |
Total formula weight | 2638.4 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 4032.2 | |
All* | Total formula weight | 102826.0 |