4WEF
Structure of the Hemagglutinin-neuraminidase from Human parainfluenza virus type III: complex with difluorosialic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hemagglutinin-neuraminidase glycoprotein | polymer | 431 | 48077.7 | 2 | UniProt (Q6WJ03) | Human parainfluenza virus 3 | |
| 2 | C, E (C, E) | beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G31886NL) | |||
| 3 | D, F (D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 4 | G, T (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | H, U (A, B) | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid | non-polymer | 327.3 | 2 | Chemie (FSI) PubChem (23628524) PubChem (23628525) PubChem (150864) PubChem (58753593) PubChem (71065668) PubChem (448471) PubChem (72206646) PubChem (91532921) PubChem (118479993) PubChem (9949281) PubChem (11450242) PubChem (14101566) PubChem (129678999) PubChem (129715278) PubChem (134972939) PubChem (135016585) PubChem (155168392) PubChem (168356717) PubChem (168373736) | |||
| 6 | I, V (A, B) | (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate | non-polymer | 309.2 | 2 | Chemie (DF4) PubChem (137349171) | |||
| 7 | J, K, W (A, B) | (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid | non-polymer | 329.3 | 3 | Chemie (SFJ) PubChem (68103580) PubChem (89708762) PubChem (91885381) PubChem (102234977) PubChem (102064038) PubChem (102234976) PubChem (118303408) PubChem (122402127) PubChem (137349368) PubChem (10381896) PubChem (14101562) PubChem (14101563) PubChem (14101564) PubChem (126496252) PubChem (170987196) | |||
| 8 | AA, BA, CA, L, M... (B, A) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 9 | DA, R (B, A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 10 | EA, FA (A, B) | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A, B: 142 - 572 (UniProt: Q6WJ03)
| PDB | External Database | Details |
|---|---|---|
| Gly 408 | Ser 408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96155.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2638.4 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 4032.2 | |
| All* | Total formula weight | 102826.0 |
