4V0U

The crystal structure of ternary PP1G-PPP1R15B and G-actin complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, L, M	ACTIN, ALPHA SKELETAL MUSCLE	polymer	375	41862.6	5	UniProt (P68135) Pfam (PF00022) In PDB	ORYCTOLAGUS CUNICULUS (RABBIT)	ALPHA-ACTIN-1, ACTIN
2	D, F, H, J, N	SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT	polymer	323	37030.8	5	UniProt (P63087) Pfam (PF16891) Pfam (PF00149) In PDB	MUS MUSCULUS (HOUSE MOUSE)	PP-1G, PROTEIN PHOSPHATASE 1C CATALYTIC SUBUNIT, PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
3	E, G, I, K, O	PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B	polymer	84	10185.4	5	UniProt (Q5SWA1) In PDB	HOMO SAPIENS (HUMAN)
4	L, M, A, B, C	LATRUNCULIN B	non-polymer		395.5	5	Chemie (LAB)
5	L, M, A, B, C	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	5	Chemie (ATP)
6	H, J, N, D, F	MANGANESE (II) ION	non-polymer		54.9	10	Chemie (MN)

Sequence modifications

E, G, I, K, O: 631 - 701 (UniProt: Q5SWA1)

PDB	External Database	Details
Gly 626	-	expression tag
Ala 627	-	expression tag
Met 628	-	expression tag
Asp 629	-	expression tag
Pro 630	-	expression tag
Leu 702	-	expression tag
Glu 703	-	expression tag
His 704	-	expression tag
His 705	-	expression tag
His 706	-	expression tag
His 707	-	expression tag
His 708	-	expression tag
His 709	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	445393.7
Non-Polymers*	Number of molecules	20
	Total formula weight	5062.8
All*	Total formula weight	450456.6

*Water molecules are not included.