4V0U
The crystal structure of ternary PP1G-PPP1R15B and G-actin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, L, M (A, B, C, L, M) | ACTIN, ALPHA SKELETAL MUSCLE | polymer | 375 | 41862.6 | 5 | UniProt (P68135) Pfam (PF00022) | ORYCTOLAGUS CUNICULUS (RABBIT) | ALPHA-ACTIN-1, ACTIN |
| 2 | D, F, H, J, N (D, F, H, J, N) | SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | polymer | 323 | 37030.8 | 5 | UniProt (P63087) Pfam (PF16891) Pfam (PF00149) | MUS MUSCULUS (HOUSE MOUSE) | PP-1G, PROTEIN PHOSPHATASE 1C CATALYTIC SUBUNIT, PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT |
| 3 | E, G, I, K, O (E, G, I, K, O) | PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B | polymer | 84 | 10185.4 | 5 | UniProt (Q5SWA1) | HOMO SAPIENS (HUMAN) | |
| 4 | DA, FA, P, R, T (L, M, A, B, C) | LATRUNCULIN B | non-polymer | 395.5 | 5 | Chemie (LAB) | |||
| 5 | EA, GA, Q, S, U (L, M, A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 6 | AA, BA, CA, HA, IA... (H, J, N, D, F) | MANGANESE (II) ION | non-polymer | 54.9 | 10 | Chemie (MN) |
Sequence modifications
E, G, I, K, O: 631 - 701 (UniProt: Q5SWA1)
| PDB | External Database | Details |
|---|---|---|
| Gly 626 | - | expression tag |
| Ala 627 | - | expression tag |
| Met 628 | - | expression tag |
| Asp 629 | - | expression tag |
| Pro 630 | - | expression tag |
| Leu 702 | - | expression tag |
| Glu 703 | - | expression tag |
| His 704 | - | expression tag |
| His 705 | - | expression tag |
| His 706 | - | expression tag |
| His 707 | - | expression tag |
| His 708 | - | expression tag |
| His 709 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 445393.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 5062.8 | |
| All* | Total formula weight | 450456.6 |
