4V05
FGFR1 in complex with AZD4547.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B | polymer | 309 | 35135.3 | 2 | UniProt (D3DSX2) In PDB | HOMO SAPIENS (HUMAN) | FGFR1 |
| 2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | A, B | N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide | non-polymer | 463.6 | 2 | Chemie (66T) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A, B: 458 - 765 (UniProt: D3DSX2)
| PDB | External Database | Details |
|---|---|---|
| Gly 457 | - | expression tag |
| Ala 488 | Cys 52 | conflict |
| Ser 584 | Cys 148 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70270.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1621.7 | |
| All* | Total formula weight | 71892.4 |
