4V05
FGFR1 in complex with AZD4547.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Detector | RIGAKU CCD |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 208.780, 57.480, 65.580 |
| Unit cell angles | 90.00, 107.64, 90.00 |
Refinement procedure
| Resolution | 28.410 - 2.570 |
| R-factor | 0.1955 |
| Rwork | 0.192 |
| R-free | 0.25560 |
| Structure solution method | OTHER |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.120 |
| Data reduction software | XDS |
| Refinement software | BUSTER (2.11.2) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 99.480 | 2.710 |
| High resolution limit [Å] | 2.570 | 2.570 |
| Rmerge | 0.060 | |
| Number of reflections | 22994 | |
| <I/σ(I)> | 15.2 | |
| Completeness [%] | 96.8 | 97.1 |
| Redundancy | 3.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
