4UYD

N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-dimethyl-2-oxo-2,3- dihydro-1H-1,3-benzodiazole-5-carboxamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	BROMODOMAIN-CONTAINING PROTEIN 4	polymer	153	17961.6	1	UniProt (O60885) Pfam (PF00439) In PDB	HOMO SAPIENS (HUMAN)	PROTEIN HUNK1
2	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	A	1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-carboxamide	non-polymer		205.2	1	Chemie (V1T)
5		water	water		18.0	275	Chemie (HOH)

Sequence modifications

A: 44 - 183 (UniProt: O60885)

PDB	External Database	Details
Gly 31	-	expression tag
Ser 32	-	expression tag
Ser 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
Ser 40	-	expression tag
Ser 41	-	expression tag
Gly 42	-	expression tag
Met 43	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17961.6
Non-Polymers*	Number of molecules	3
	Total formula weight	345.4
All*	Total formula weight	18307.0

*Water molecules are not included.