4UXB
Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor PJ34
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | POLY ADP-RIBOSE POLYMERASE 1 | polymer | 352 | 39387.1 | 2 | UniProt (P09874) Pfam (PF02877) Pfam (PF00644) | HOMO SAPIENS (HUMAN) | PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1, ARTD1, NAD(+) ADP-RIBOSYLTRANSFERASE 1, ADPRT 1, POLYADP-RIBOSEH SYNTASE 1, POLY ADP-RIBOSE POLYMERASE 1 |
| 2 | C, E (A, B) | N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | non-polymer | 295.3 | 2 | Chemie (P34) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B: 662 - 1011 (UniProt: P09874)
| PDB | External Database | Details |
|---|---|---|
| Ser 660 | - | expression tag |
| Met 661 | - | expression tag |
| Ala 762 | Val 762 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78774.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 686.7 | |
| All* | Total formula weight | 79460.9 |
