4UXB
Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor PJ34
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE P34 A 2011 |
| Chain | Residue |
| A | GLU763 |
| A | HIS862 |
| A | GLY863 |
| A | GLY888 |
| A | TYR896 |
| A | SER904 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE P34 B 2010 |
| Chain | Residue |
| B | TYR896 |
| B | PHE897 |
| B | SER904 |
| B | TYR907 |
| B | GLU988 |
| B | HIS862 |
| B | GLY863 |
| B | TYR889 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2012 |
| Chain | Residue |
| A | LYS838 |
| A | LYS1000 |
| B | GLN846 |
| B | LYS849 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For poly [ADP-ribose] polymerase activity","evidences":[{"source":"PubMed","id":"32028527","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"7852410","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9315851","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9UGN5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
