4URT
The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NETRIN-1 | polymer | 420 | 47484.5 | 1 | UniProt (O95631) Pfam (PF00055) Pfam (PF00053) | HOMO SAPIENS (HUMAN) | EPIDIDYMIS TISSUE PROTEIN LI 131P |
| 2 | B (B) | NETRIN RECEPTOR DCC | polymer | 206 | 23243.6 | 1 | UniProt (P43146) Pfam (PF00041) | HOMO SAPIENS (HUMAN) | COLORECTAL CANCER SUPPRESSOR, IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 1, TUMOR SUPPRESSOR PROTEIN DCC, DELETED IN COLORECTAL CANCER |
| 3 | C, D, E (C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | H, I, J, K, L... (A, B) | SULFATE ION | non-polymer | 96.1 | 17 | Chemie (SO4) | |||
| 7 | Y (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) |
Sequence modifications
A: 39 - 453 (UniProt: O95631)
B: 844 - 1043 (UniProt: P43146)
| PDB | External Database | Details |
|---|---|---|
| Glu 454 | - | expression tag |
| Leu 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 1045 | - | expression tag |
| Glu 1046 | - | expression tag |
| Val 1047 | - | expression tag |
| Leu 1048 | - | expression tag |
| Phe 1049 | - | expression tag |
| Ala 1050 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70728.1 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1800.7 | |
| All* | Total formula weight | 73802.0 |
