4URT

The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005042	molecular_function	netrin receptor activity
B	0006915	biological_process	apoptotic process
B	0007399	biological_process	nervous system development
B	0007411	biological_process	axon guidance

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CdCrhNtaGPeC

Chain	Residue	Details
A	CYS304-CYS315
A	CYS423-CYS434

---

site_id	PS01248
Number of Residues	35
Details	EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cd.CrhntaGpeCdrCkpfhYdrpwqratareane.C

Chain	Residue	Details
A	CYS304-CYS338
A	CYS368-CYS404
A	CYS423-CYS451

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	237
Details	Domain: {"description":"Laminin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00466","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	55
Details	Domain: {"description":"Laminin EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	62
Details	Domain: {"description":"Laminin EGF-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	49
Details	Domain: {"description":"Laminin EGF-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	96
Details	Domain: {"description":"Fibronectin type-III 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	97
Details	Domain: {"description":"Fibronectin type-III 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---