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4UIS

The cryoEM structure of human gamma-Secretase complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GAMMA-SECRETASEpolymer58863332.01Pfam (PF18266)
Pfam (PF05450)
UniProt (by SIFTS) (Q92542)
HOMO SAPIENS (HUMAN)
2B
(B)
GAMMA-SECRETASEpolymer24123547.61UniProt (by SIFTS) (P49768)HOMO SAPIENS (HUMAN)
3C
(C)
GAMMA-SECRETASEpolymer19616698.51HOMO SAPIENS (HUMAN)
4D
(D)
GAMMA-SECRETASEpolymer625294.51HOMO SAPIENS (HUMAN)
5E
(G)
LYSOZYMEpolymer16218435.21UniProt (A0A097J809)
Pfam (PF00959)
UniProt (by SIFTS) (D9IEF7)
HOMO SAPIENS (HUMAN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight127307.9
All*Total formula weight127307.9
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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