4UI0
Crystal structure of the human RGMB-BMP2 complex, crystal form 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BONE MORPHOGENETIC PROTEIN 2 | polymer | 114 | 12923.9 | 2 | UniProt (P12643) Pfam (PF00019) | HOMO SAPIENS (HUMAN) | BMP-2, BONE MORPHOGENETIC PROTEIN 2A, BMP-2A, BMP2 |
| 2 | C (C) | RGM DOMAIN FAMILY MEMBER B | polymer | 96 | 10532.7 | 1 | UniProt (Q6NW40) Pfam (PF06535) | HOMO SAPIENS (HUMAN) | DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE, DRAGON, REPULSIVE GUIDANCE MOLECULE B, RGMB |
| 3 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | E (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 5 | F (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
C: 53 - 136 (UniProt: Q6NW40)
| PDB | External Database | Details |
|---|---|---|
| Glu 50 | - | expression tag |
| Thr 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Gly 137 | - | expression tag |
| Thr 138 | - | expression tag |
| Lys 139 | - | expression tag |
| His 140 | - | expression tag |
| His 141 | - | expression tag |
| His 142 | - | expression tag |
| His 143 | - | expression tag |
| His 144 | - | expression tag |
| His 145 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 36380.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 342.7 | |
| All* | Total formula weight | 36723.1 |
