4UEC

Complex of D. melanogaster eIF4E with eIF4G and cap analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	polymer	184	21249.0	2	UniProt (P48598) Pfam (PF01652)	DROSOPHILA MELANOGASTER (FRUIT FLY)	EIF4E, EIF-4F 25 KDA SUBUNIT, MRNA CAP-BINDING PROTEIN
2	B (B)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ISOFORM A	polymer	78	8871.0	1	UniProt (O61380) Pfam (PF21140)	DROSOPHILA MELANOGASTER (FRUIT FLY)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ISOFORM C, FI02056P, TRANSLATION INITIATION FACTOR EIF4G
3	D, E (A, C)	7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE	non-polymer		539.2	2	Chemie (MGT)
4	F, G, H (A, B, C)	water	water		18.0	44	Chemie (HOH)

Sequence modifications

A, C: 69 - 248 (UniProt: P48598)

PDB	External Database	Details
Gly 65	-	expression tag
Pro 66	-	expression tag
His 67	-	expression tag
Met 68	-	expression tag

B: 578 - 650 (UniProt: O61380)

PDB	External Database	Details
Gly 573	-	expression tag
His 574	-	expression tag
Met 575	-	expression tag
Leu 576	-	expression tag
Glu 577	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	51369.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1078.4
All*	Total formula weight	52447.5

*Water molecules are not included.