4UEC

Complex of D. melanogaster eIF4E with eIF4G and cap analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005737	cellular_component	cytoplasm
A	0006413	biological_process	translational initiation
C	0003723	molecular_function	RNA binding
C	0003743	molecular_function	translation initiation factor activity
C	0005737	cellular_component	cytoplasm
C	0006413	biological_process	translational initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MGT C 1237

Chain	Residue
C	TRP89
C	MET134
C	TRP135
C	GLU136
C	ARG188
C	LYS193
C	HOH2017
C	HOH2026

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MGT A 1237

Chain	Residue
A	MET134
A	TRP135
A	GLU136
A	ARG188
A	LYS193
C	LEU208
A	TRP89

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Functional Information from PROSITE/UniProt

site_id	PS00813
Number of Residues	24
Details	IF4E Eukaryotic initiation factor 4E signature. DYslFKknIrPmWEDaankqGGRW

Chain	Residue	Details
A	ASP123-TRP146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P06730

Chain	Residue	Details
A	TRP89
A	TRP135
A	ARG188
C	TRP89
C	TRP135
C	ARG188

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