4U3J

TOG2:alpha/beta-tubulin complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tubulin alpha-1 chain	polymer	447	49853.9	1	UniProt (P09733) Pfam (PF00091) Pfam (PF03953)	Saccharomyces cerevisiae (Baker's yeast)
2	B (B)	Tubulin beta chain	polymer	463	51910.5	1	UniProt (P02557) Pfam (PF00091) Pfam (PF03953)	Saccharomyces cerevisiae (Baker's yeast)	Beta-tubulin
3	C (C)	Protein STU2	polymer	249	28827.4	1	UniProt (P46675)	Saccharomyces cerevisiae (Baker's yeast)	Suppressor of tubulin 2
4	D, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	E, G (A, B)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	H, I, J (A, B, C)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

B: 1 - 457 (UniProt: P02557)

PDB	External Database	Details
Arg 175	Thr 175	engineered mutation
Arg 179	Val 179	engineered mutation
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag

C: 318 - 560 (UniProt: P46675)

PDB	External Database	Details
His 561	-	expression tag
His 562	-	expression tag
His 563	-	expression tag
His 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	130591.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1095.0
All*	Total formula weight	131686.7

*Water molecules are not included.