4U2R

Crystal structure of the GLUR2 ligand binding core (S1S2J, flip variant) in the apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	Glutamate receptor 2	polymer	263	29193.7	4	UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2	B, D	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3		water	water		18.0	1952	Chemie (HOH)

Sequence modifications

B, A, C, D: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 2	-	expression tag

B, A, C, D: 120 - 263 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Ser 263	Ala 796	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	116774.7
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	116966.8

*Water molecules are not included.