4U0M
Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D193N in complex with ATP, GTP and 5MTHFGLU2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cyclic AMP-GMP synthase | polymer | 427 | 48824.4 | 2 | UniProt (Q9KVG7) Pfam (PF21654) Pfam (PF21713) In PDB | Vibrio cholerae El Tor N16961 | c-AMP-GMP synthase,Dinucleotide cyclase DncV |
2 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
3 | A, B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | A | N-[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-glutamic acid | non-polymer | 588.6 | 1 | Chemie (TLL) | |||
6 | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 419 (UniProt: Q9KVG7)
PDB | External Database | Details |
---|---|---|
Asn 193 | Asp 193 | engineered mutation |
Leu 420 | - | expression tag |
Glu 421 | - | expression tag |
His 422 | - | expression tag |
His 423 | - | expression tag |
His 424 | - | expression tag |
His 425 | - | expression tag |
His 426 | - | expression tag |
His 427 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 97648.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2697.9 | |
All* | Total formula weight | 100346.7 |