4U03
Structure of the vibrio cholerae di-nucleotide cyclase (DncV) in complex with GTP and 5MTHFGLU2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic AMP-GMP synthase | polymer | 427 | 48825.4 | 2 | UniProt (Q9KVG7) Pfam (PF21654) Pfam (PF21713) | Vibrio cholerae El Tor N16961 | c-AMP-GMP synthase, Dinucleotide cyclase DncV |
| 2 | C, D, H, I (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 3 | E, F, J, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | G, L (A, B) | N-[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-glutamic acid | non-polymer | 588.6 | 2 | Chemie (TLL) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 419 (UniProt: Q9KVG7)
| PDB | External Database | Details |
|---|---|---|
| Leu 420 | - | expression tag |
| Glu 421 | - | expression tag |
| His 422 | - | expression tag |
| His 423 | - | expression tag |
| His 424 | - | expression tag |
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97650.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3367.1 | |
| All* | Total formula weight | 101017.9 |
