4TYJ
Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fibroblast growth factor receptor 4 | polymer | 311 | 34689.1 | 1 | UniProt (P22455) Pfam (PF07714) | Homo sapiens (Human) | FGFR-4 |
| 2 | B (A) | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide | non-polymer | 532.6 | 1 | Chemie (0LI) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | F (A) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A: 447 - 753 (UniProt: P22455)
| PDB | External Database | Details |
|---|---|---|
| Ala 443 | - | expression tag |
| Met 444 | - | expression tag |
| Gly 445 | - | expression tag |
| Ser 446 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34689.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 784.6 | |
| All* | Total formula weight | 35473.6 |
