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4TUU

Isolated p110a subunit of PI3Ka provides a platform for structure-based drug design

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformpolymer946109983.11UniProt (P42336)
Pfam (PF00794)
Pfam (PF00792)
Pfam (PF00613)
Pfam (PF00454)
In PDB
Homo sapiens (Human)PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,p110alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA
2waterwater18.030Chemie (HOH)
Sequence modifications
A: 105 - 1048 (UniProt: P42336)
PDBExternal DatabaseDetails
Gly 103-expression tag
Ser 104-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight109983.1
All*Total formula weight109983.1
*Water molecules are not included.

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PDB entries from 2024-09-18

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