4TUU
Isolated p110a subunit of PI3Ka provides a platform for structure-based drug design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | polymer | 946 | 109983.1 | 1 | UniProt (P42336) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | Homo sapiens (Human) | PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,p110alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA |
| 2 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 105 - 1048 (UniProt: P42336)
| PDB | External Database | Details |
|---|---|---|
| Gly 103 | - | expression tag |
| Ser 104 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 109983.1 | |
| All* | Total formula weight | 109983.1 |
